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  • Title: Double-blind study of levamisole in aphthous stomatitis.
    Author: Kaplan B, Cardarelli C, Pinnell SR.
    Journal: J Oral Pathol; 1978; 7(6):400-4. PubMed ID: 105099.
    Abstract:
    Sixty-five patients with recurrent aphthous stomatitis participated in a double-blind study to evaluate levamisole. Nineteen of 34 patients improved on levamisole and only five of 31 patients improved on placebo (P less than 0.004, chi-square with two degrees of freedom). After breaking the code and switching placebo patients to levamisole and non-responders to an alternate dosage schedule, 46 of 60 patients noted clinical improvement.
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