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  • Title: Microbial hydroxylation of natural drimenic lactones.
    Author: Maurs M, Azerad R, Cortés M, Aranda G, Delahaye MB, Ricard L.
    Journal: Phytochemistry; 1999 Sep; 52(2):291-6. PubMed ID: 10513402.
    Abstract:
    Incubation of confertifolin and isodrimenin with Mucor plumbeus, Aspergillus niger or Rhizopus arrhizus gave in good yields the corresponding 3 beta-hydroxy derivatives. From isodrimenin, the known natural 7 alpha-hydroxy derivative (futronolide) was also obtained and its structure was definitely established by X-ray crystallographic study of its acetate derivative.
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