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  • Title: A combination of autoimmune hepatitis, sensory-dominant peripheral neuropathy, and primary Sjögren's syndrome in the same patient: a rare association.
    Author: Hoshino S, Yoshizawa T, Hayashi A, Ohkoshi N, Tamaoka A, Shoji S.
    Journal: J Med; 1999; 30(1-2):83-92. PubMed ID: 10515244.
    Abstract:
    Although autoimmune hepatitis and sensory-dominant neuropathy have been known to independently accompany primary Sjögren's syndrome, the combination of all these conditions in the same patient has not been described. We report the case of a woman who initially suffered from autoimmune hepatitis and later was diagnosed with primary Sjogren's syndrome upon the development of sensory-dominant neuropathy. In this patient, autoimmune hepatitis preceded neuropathy by one year. All of the diagnoses were confirmed by histological examinations of the liver, sural nerve, and minor salivary gland. Her autoimmune hepatitis was relieved with conservative treatment, and her sensory-dominant neuropathy was alleviated by prednisolone therapy. Our case indicated that the multiple organ involvement, especially that in the liver and peripheral nerves, should be taken into account in the course of primary Sjögren's syndrome.
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