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  • Title: Keloids and hypertrophic scars: results with intraoperative and serial postoperative corticosteroid injection therapy.
    Author: Chowdri NA, Masarat M, Mattoo A, Darzi MA.
    Journal: Aust N Z J Surg; 1999 Sep; 69(9):655-9. PubMed ID: 10515339.
    Abstract:
    BACKGROUND: The management of keloids and hypertrophic scars continues to be controversial. Experience of treating 58 such lesions, 58.62% of which were recurrent, is presented. METHODS: Each lesion was subjected to surgical excision with intra-operative local injection of triamcinolone acetonide, followed by repeat injection of the same drug at weekly intervals for 2-5 weeks depending on the symptomatic relief, and then monthly injections for 4-6 months. RESULTS: Complete symptomatic relief was achieved in all patients within 5 weeks of surgery. Objective response in terms of no recurrence was noted in 91.9% of patients with keloids, and 95.24% of patients with hypertrophic scars at a mean follow-up of 30.5 months. Local or systemic complications were insignificant. CONCLUSION: Because of promising results, further use and evaluation of this method of treatment is recommended for large, recurrent and complicated keloids and hypertrophic scars.
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