These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The immunopathogenesis of multiple sclerosis. A survey of recent advances and implications for future therapy.
    Author: Kieseier BC, Archelos JJ, Storch M, Gold R, Hartung HP.
    Journal: Wien Klin Wochenschr; 1999 Sep 17; 111(17):728-37. PubMed ID: 10526397.
    Abstract:
    The etiology of multiple sclerosis (MS) still remains elusive. However, the association of the disease with relevant genes, the characteristic white matter infiltrates, similarities with animal models, and the fact that MS can be treated with immunomodulatory and immunosuppressive therapies support the notion that this disorder is autoimmune in nature. During the last few years the knowledge about the mechanisms involved in the pathogenesis of MS increased rapidly. In this review, recent advances in our understanding about relevant pathomechanisms in inflammatory demyelinating diseases of the central nervous system will be discussed and the rational of some novel immunotherapies is explained in context of the current understanding of immunological principles.
    [Abstract] [Full Text] [Related] [New Search]