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  • Title: Long-term re-treatment with interferon and ribavirin combination therapy in patients with chronic hepatitis C who are non-responders to interferon alone: a preliminary study.
    Author: Vega P, Castro A, Hermida M, López Calvo S, Pedreira J.
    Journal: Scand J Infect Dis; 1999; 31(4):359-61. PubMed ID: 10528873.
    Abstract:
    We evaluated the efficacy and tolerance of ribavirin and IFN-alpha combination therapy over 12 months in 28 patients who were non-responders to IFN-alpha alone. Of 24 patients who have finished the therapy, 6 (25%) obtained a complete response (normal ALT and negative HCV RNA) at the end of treatment and maintained a sustained response 27% (5/18).
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