These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Synthesis and antifungal activity of coumarins and angular furanocoumarins.
    Author: Sardari S, Mori Y, Horita K, Micetich RG, Nishibe S, Daneshtalab M.
    Journal: Bioorg Med Chem; 1999 Sep; 7(9):1933-40. PubMed ID: 10530942.
    Abstract:
    Angelicin, a naturally occurring furanocoumarin, that showed antifungal activity, was considered as a lead structure for a group of synthetic coumarins. Antifungal activities of the synthesized coumarins and angelicin derivatives were reported against Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisiae and Aspergillus niger. Human cell line cytotoxicity of several coumarins was evaluated against KB cells. Angelicin and several potent antifungals showed to be non-toxic in this assay.
    [Abstract] [Full Text] [Related] [New Search]