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  • Title: Giant cell reparative granuloma: a case report.
    Author: Chen SS, Chiang JH, Chang CY, Lao CB, Lirng JF, Teng MM.
    Journal: Zhonghua Yi Xue Za Zhi (Taipei); 1999 Oct; 62(10):738-42. PubMed ID: 10533306.
    Abstract:
    Giant cell reparative granuloma (GCRG) is an infrequent benign lesion with undetermined etiopathogenesis affecting the maxillary and mandibular bone and, rarely, the skull. It is also extremely rare in the sphenoid bone. GCRG is usually diagnosed by histologic examination of bone lesions. We report a case of GCRG originating from the sphenoid bone. Computerized tomography revealed an expansile lesion with thinning or destruction of the cortical bone. The lesion itself was slightly hyperdense with good but inhomogeneous contrast enhancement. Reported magnetic resonance image findings showed hyperintensity on both T1-weighted and T2-weighted images and variable contrast enhancement. Plain skull radiographs usually reveal a lytic lesion within the bone.
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