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  • Title: Pneumonectomy in cystic fibrosis.
    Author: Häusler M, Franke E, Wendt G, Kentrup H, Döhmen H, Kusenbach G.
    Journal: Pediatr Pulmonol; 1999 Nov; 28(5):376-9. PubMed ID: 10536069.
    Abstract:
    A 17-year-old boy and a 12-year-old girl with cystic fibrosis (forced expiratory volume in 1 sec, 36% and 14% of predicted values, respectively) developed severe right-sided lung infections with abscess formations and complete atelectases unresponsive to medical therapy. In both patients, unilateral emergency pneumonectomy resulted in rapid clinical improvement. Despite her severe underlying lung disease, the girl experienced a remarkable increase in quality of life; 2 years after surgery, she died from respiratory failure. The male patient has now survived for 4 years, and lung transplantation still remains a therapeutic option for him. We believe that pneumonectomy is a valuable rescue therapy for patients with cystic fibrosis and intractable unilateral lung infections who are at high risk of dying while waiting for lung transplantation.
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