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  • Title: Co-distribution of sensory gating and impaired niacin flush response in the parents of schizophrenics.
    Author: Waldo MC.
    Journal: Schizophr Res; 1999 Nov 09; 40(1):49-53. PubMed ID: 10541007.
    Abstract:
    Complex illnesses may result from the interaction or addition of multiple factors. We examined the familial co-distribution of two abnormalities common in schizophrenia: impaired auditory sensory gating and impaired flush response to niacin. In ten families, the obligate carrier parent had sensory-gating deficits, while eight of the ten parents without a family history of schizophrenia had impaired flush response. No parents had both deficits. The data are consistent with a theory suggesting the interaction of these two factors in some cases of schizophrenia.
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