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Title: Isolation of xestosterol esters of brominated acetylenic fatty acids from the marine sponge xestospongia testudinaria. Author: Pham NB, Butler MS, Hooper JN, Moni RW, Quinn RJ. Journal: J Nat Prod; 1999 Oct; 62(10):1439-42. PubMed ID: 10543913. Abstract: The CH(2)Cl(2) extract of the marine sponge Xestospongia testudinaria inhibited [(3)H]DPCPX binding to rat-brain adenosine A(1) receptors. Bioassay-guided fractionation led to the isolation of a known brominated acetylenic fatty acid 1 as the active component. Also isolated were two novel sterol esters 2 and 3. All structures were determined on the basis of their spectroscopic data.[Abstract] [Full Text] [Related] [New Search]