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  • Title: Craniofacial variability in parents of children with cleft lip and cleft palate.
    Author: AlEmran SE, Fatani E, Hassanain JE.
    Journal: J Clin Pediatr Dent; 1999; 23(4):337-41. PubMed ID: 10551135.
    Abstract:
    The purpose of this study was to determine whether there are variations in the craniofacial morphology between parents of children with non-syndromic cleft lip and palate and normal controls with no history of cleft in the families in a Saudi sample. Frontal skull radiographs were obtained from a study group consisting of 40 couples, who have a child with cleft deformity and control group of 32 males and 35 females, who have no history of clefts in the family. A total of 18 landmarks were digitized for each individual by a custom made computer program. T-test, logistic regression analysis were applied to the data. Significant findings were obtained for both males and females of the affected children. The males displayed wider nasal cavity and a narrower maxillary width with asymmetry of the face. Females showed smaller facial dimension as a whole, and asymmetry of the face.
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