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  • Title: [Clinical evaluation of weekly hepatic arterial infusion chemotherapy in patients with unresectable metastatic liver cancer].
    Author: Kunishima S, Taniguchi H, Koh T, Yamaguchi A, Okamoto K, Shirasu M, Otsuji E, Kitamura K, Hagiwara A, Yamaguchi T, Yamagishi H.
    Journal: Gan To Kagaku Ryoho; 1999 Oct; 26(12):1768-71. PubMed ID: 10560391.
    Abstract:
    Twenty-five cases with unresectable metastatic liver cancers were experienced in our hospital over the past five years who underwent weekly 24-hour continuous hepatic arterial infusion chemotherapy using 5-FU and CBDCA. The response rate was 20%, the median survival was 23 months, and the one/two year overall survival rates averaged 81.3/45.5%. In 77% of patients, this therapy prevented death from hepatic metastases. Moreover, since adverse effects were limited compared with bolus infusion, weekly 24-hour continuous hepatic arterial infusion chemotherapy was thought to be a favorable method.
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