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  • Title: [Present possibilities of prevention of adhesions and their immunologic aspects].
    Author: Crha I, Ventruba P, Petrenko M, Visnová H.
    Journal: Ceska Gynekol; 1999 Jul; 64(4):230-4. PubMed ID: 10568060.
    Abstract:
    The study reviews recent developments with regard to postsurgical adhesion formation, the role of some cytokines and possible prevention. Interleukin-1 beta (IL-1 beta) levels in peritoneal fluid were assayed during 24 and 48 hours after laparoscopic or laparotomic surgery and the influence of diclofenac was evaluated. IL-1 beta levels in peritoneal fluid were substantially lower after laparoscopic adnexal surgery than after laparotomy. Application of diclofenac after abdominal hysterectomies reduced substantially intraperitoneal IL-1 beta levels.
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