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  • Title: Longitudinal melanonychia associated with hydroxyurea therapy in a patient with essential thrombocytosis.
    Author: Cohen AD, Hallel-Halevy D, Hatskelzon L, Peretz E, Halevy S.
    Journal: J Eur Acad Dermatol Venereol; 1999 Sep; 13(2):137-9. PubMed ID: 10568495.
    Abstract:
    Occurrence of skin lesions during long-term therapy with hydroxyurea are well described, but there have been only a few case reports of longitudinal melanonychia associated with hydroxyurea treatment. We report herein longitudinal melanonychia associated with hydroxyurea therapy in a subject with essential thrombocytosis. The prolonged time lapse (1 year) between initiation of hydroxyurea therapy and the onset of the longitudinal melanonychia should be noted.
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