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  • Title: The effect of long-term training on age-related left ventricular changes by Doppler myocardial velocity gradient.
    Author: Palka P, Lange A, Nihoyannopoulos P.
    Journal: Am J Cardiol; 1999 Nov 01; 84(9):1061-7. PubMed ID: 10569664.
    Abstract:
    Myocardial velocity gradient (MVG) derived from Doppler myocardial imaging and standard echocardiographic parameters were used to investigate whether age-related left ventricular (LV) functional and/or structural changes are different in long-term training athletes than in those leading a sedentary life style. Eighty-nine athletes (64 men, mean age 38 years, range 18 to 64) and 105 age-matched sedentary normal subjects were enrolled into the study. The MVG was analyzed in all patients throughout the cardiac cycle, and peak values were measured in systole and in diastole during both rapid ventricular filling and atrial contraction. No differences were found in LV systolic and late diastolic function between athletes and sedentary normal subjects. However, athletes had higher peak E waves in early diastole (73 +/- 10 cm/s vs 68 +/- 10 cm/s, p <0.001) and rapid ventricular filling MVG (10.2 +/- 1.5 s(-1) vs 7.2 +/- 2.8 s(-1), p <0.001) than sedentary normal subjects, suggesting a better early relaxation pattern. From LV diastolic indexes, the rapid ventricular filling MVG age-related decrease was less pronounced in athletes than in sedentary normal subjects (r = -0.39 vs r = -0.91; p <0.01). All other diastolic variables, including transmitral Doppler inflow, had a similar degree of age-related changes in both study groups. Thus, athletes, compared with those leading a sedentary lifestyle, have higher early diastolic performance, which is less affected by the physiologic aging process. It would appear that MVG derived from Doppler myocardial imaging may play an important role in the assessment of LV functional and/or structural changes.
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