These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [The effect of pregna-D'-pentarans on myometrial contractile activity in pregnant rats].
    Author: Kareva EN, Kamernitskiĭ AV, Levina LS, Solov'eva EV, Kirpichnikova NV, Isaeva SA.
    Journal: Eksp Klin Farmakol; 1999; 62(5):25-7. PubMed ID: 10572747.
    Abstract:
    The authors studied the effect of synthetic gestagens on spontaneous contractility of the myometrium in pregnant rats. The direction of the effect of progesterone and its analogs on the contractility is determined by stereochemistry of the linkage of rings A and B of the steroid molecule. Compounds possessing translinkage (5 beta-steroids) increase the amplitude of myometrium contraction, whereas their analogs with cms-coupling of rings A and B (5 alpha-steroids), and 4,5-unsaturated steroids reduce it.
    [Abstract] [Full Text] [Related] [New Search]