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  • Title: [Combined radiotherapy and chemotherapy of the central nervous system in malignant neoplasms of children (author's transl)].
    Author: Gutjahr P, Kutzner J.
    Journal: Dtsch Med Wochenschr; 1975 Aug 15; 100(33):1651-6. PubMed ID: 1057505.
    Abstract:
    A combination of radiotherapy and cytostatic drugs was used in the treatment of 39 children with primary brain tumour between 1961 and 1974, and 40 children with acute lymphoid leukaemia between 1971 and 1974. Best results were obtained with medulloblastoma using cerebrospinal radiotherapy and cytostatic drugs: 10 of 17 children are still alive. Of 40 children with acute lymphoid leukaemia 18 are still alive after cerebrospinal or cranial radiotherapy. The side effects of the combined therapy were within justifiable limits.
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