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  • Title: Asymmetric expression of antivin/lefty1 in the early chick embryo.
    Author: Ishimaru Y, Yoshioka H, Tao H, Thisse B, Thisse C, V E Wright C, Hamada H, Ohuchi H, Noji S.
    Journal: Mech Dev; 2000 Jan; 90(1):115-8. PubMed ID: 10585569.
    Abstract:
    Mammalian lefty and zebrafish antivin, highly related to lefty, are shown to be expressed asymmetrically and involved in the specification of the left body side of early embryos. We isolated a chick homologue of the antivin/lefty1 cDNA and studied its expression pattern during early chick development. We found that antivin/lefty1 is expressed asymmetrically on the left side of the prospective floorplate, notochord and lateral plate mesoderm of the chick embryo.
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