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  • Title: Tongue necrosis provoked by ergotamine tartrate and disclosing a giant cell arteritis.
    Author: Stoebner PE, Gaspard C, Meynadier J, Meunier L.
    Journal: Eur J Dermatol; 1999 Dec; 9(8):652-3. PubMed ID: 10586137.
    Abstract:
    A case of tongue necrosis induced by ergotamine tartrate is reported in a patient who was suffering from an unknown giant cell arteritis (GCA). The role of ergotamine in provoking tongue necrosis in temporal arteritis has only infrequently been considered. The hypothesis concerning ergotamine-induced vasospasm potentially being able to trigger a tongue necrosis in GCA is supported by the present case. This unusual complication warns us against uncritical prescription of this drug for elderly people suffering from migraine without considering GCA.
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