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  • Title: In vitro attachment of human gingival fibroblasts to root surfaces.
    Author: Aleo JJ, De Renzis FA, Farber PA.
    Journal: J Periodontol; 1975 Nov; 46(11):639-45. PubMed ID: 1058944.
    Abstract:
    Human gingival fibroblasts were used to study the in vitro attachment of cells to the root surface of periodontally-involved teeth. The portion of the root exposed to the disease process had little or no cell attachment; on the remainder of the root, the cells attached normally. Prior extraction of the roots with phenol-water or the mechanical removal of diseased cementum allowed the cells to attach normally. All things being equal, the extrapolation of these data to an in vivo situation dictates that a clinical success would depend upon complete removal of toxic materials from diseased cementum or the removal of the cementum itself.
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