These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Optic neuropathy in sheep associated with overdosage of closantel.
    Author: Borges AS, Mendes LC, de Andrade AL, Machado GF, Peiro JR.
    Journal: Vet Hum Toxicol; 1999 Dec; 41(6):378-80. PubMed ID: 10592945.
    Abstract:
    This report describes clinical and pathological findings in 2 flocks in Brazil where blindness and deaths in sheep occurred after closantel overdosage. Depression, weakness, and blindness affected 37 animals and 17 died in 2 flocks of 190 animals. Two animals submitted for ophthalmic examination showed no inflammation in the anterior segment of both eyes; posterior segment evaluation by indirect ophthalmoscopy suggested retinal degeneration. One postmortem evaluation local spongy vacuolization was in several regions of the brain and the optical nerves had severe axonal degeneration.
    [Abstract] [Full Text] [Related] [New Search]