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  • Title: (N-Barbituryl)phenyl- and cyclohexylalkanoic acids and some of their derivatives as potential anti-inflammatory agents.
    Author: Stankiewicz K, Bobrański B.
    Journal: Farmaco Sci; 1978 Oct; 33(10):729-39. PubMed ID: 105934.
    Abstract:
    A series of p-(N-barbituryl)phenyl- and cyclohexylalkanoic acids and their esters were synthesized. The preliminary pharmacological screening using the carrageenin, xylene and cotton tests revealed strong anti-inflammatory activity of several compounds in some of the tests performed, compound (Ij) being active in all the tests.
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