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  • Title: ["Maternal floor infarct", simultaneous manifestation of intrauterine fetal retardation and high maternal AFP level].
    Author: Görbe E, Rigó J, Marton T, Köhalmi B, Csabay L, Csapó Z.
    Journal: Z Geburtshilfe Neonatol; 1999; 203(5):218-20. PubMed ID: 10596416.
    Abstract:
    High AFP level (386.9 ng/ml) at the 16th gestational week in a 23-year old pregnant woman was observed. Fetal malformations or maternal causes could not be detected. Monitoring of fetal development and that of the fetal heart rate showed a worsening intrauterine growth retardation (IUGR). Due to the chronic hypoxia and IUGR cesarean section was performed in the 32nd gestational week and a 960 g female newborn was delivered. Histological examination of the placenta showed signs of maternal floor infarct (MFI): intervillous fibrin netlike deposition with the increase of extravillous trophoblast (X cells) and septal cystic formation. High unexplained AFP level and IUGR can draw attention to the possibility of intrauterine fetal demise, which indicates intensive intrauterine fetal monitoring.
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