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  • Title: Frozen section of lymph nodes in uterine cervical carcinoma.
    Author: Morice P, Sabourin JC, Castaigne D, Mercier S, Pautier P, Spatz A, Duvillard P, Michel G.
    Journal: Clin Exp Pathol; 1999; 47(5):223-6. PubMed ID: 10598370.
    Abstract:
    UNLABELLED: The aim of this study was to evaluate the accuracy of frozen section examination of lymph nodes in cervical cancer. METHODS: This retrospective study was based on 55 patients with stage Ib or IIa invasive cervical carcinoma treated by surgery followed by irradiation. All patients underwent a pelvic lymphadenectomy with frozen section analysis of lymph nodes. RESULTS: A total of 1249 nodes were removed (23 per patient) and 501 nodes (40%) were examined during the frozen section analysis. The sensitivity of frozen sections analysis in detecting metastatic nodes was 89%, its specificity and positive predictive value was 100% and its negative predictive value was 97%. CONCLUSIONS: The frozen section diagnosis of pelvic nodes should be performed in patients with a small cervical carcinoma to avoid systematic para-aortic lymphadenectomy. This is an accurate procedure and should be carried out on obturator, external iliac and common iliac nodes.
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