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Title: [The effect of cytochrome c on the myocardium during reperfusion]. Author: Boiarinov GA, Iakovlev AIu, Teziaeva SA, Mukhina IV, Boiarinova LV. Journal: Patol Fiziol Eksp Ter; 1999; (4):20-5. PubMed ID: 10598459. Abstract: Experimental and clinical trials have shown high effectiveness of cytochrome c (0.5 mg/kg) in prevention of reperfusion myocardial disorders in cardiosurgical patients. Cytochrome c inhibits development of myocardial ischemic contracture, depression of coronary circulation, activation of lipid peroxidation. It reduces myocardial consumption of oxygen and promotes earlier restoration of fatty acids metabolism under lower glucose consumption by the heart muscle. By correction of myocardial metabolism, the drug suppresses fermentemia in early reperfusion.[Abstract] [Full Text] [Related] [New Search]