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  • Title: Orelox (cefodoxime) in typhoid fever.
    Author: Dhanjee A, Sheikh MA, Yaqub M, Alam SE.
    Journal: J Pak Med Assoc; 1999 Jun; 49(6):148-9. PubMed ID: 10599198.
    Abstract:
    OBJECTIVE: To study the efficacy of Orelox (Cefodoxime) in Typhoid fever in children. SETTINGS: Open, non-comparative, multicentre study carried out in GP settings in various cities of Pakistan. PATIENTS: Children aged 1-15 years were included in the study. Positive Widal test was the only diagnostic inclusion criteria. RESULTS: Four centers participated in the study. Of the total 77 patients (51 males and 26 females), 61 (79%) cured, 5 (7%) improved (less severe signs and symptoms) and 11 (14%) failures. CONCLUSION: Treatment of typhoid fever in this study showed 86% efficacy in producing clinical responses suggesting that this drug can be effectively and safely used in the treatment of typhoid fever in children.
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