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  • Title: [Action of calcitonin in experimental periodontolysis in the golden hamster].
    Author: Kerebel B, Daculsi G.
    Journal: J Biol Buccale; 1975 Dec; 3(4):289-300. PubMed ID: 1060624.
    Abstract:
    48 male goldern hamsters 5 weeks old were divided in 4 groups. The first group was used as control. The second was submitted to the 2 000 cariogenic Keyes diet inducing severe alveolar bone resorption. The third and fourth group received with the same diet a thyrocalcitonin injection every two days (3rd group) and every day (4th group) during three months. The study of the alveolar plates with the scanning electron microscope in the animal having received thyrocalcitonin showed a reduced number of resorption lacunae, a denser bone surface covered by a homogeneous and dense granular material similar to that observed in the controls. The calcified globules, constituting the bone anchoring of the Sharpey's fibres, were different from those of the second group submitted to Keyes diet and similar to the controls.
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