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  • Title: Ringing changes to the 'bell-shaped curve'.
    Author: Bootman MD, Lipp P.
    Journal: Curr Biol; 1999 Dec 02; 9(23):R876-8. PubMed ID: 10607554.
    Abstract:
    The 'bell-shaped' curve relating cytosolic Ca(2+) concentration to IP(3) receptor activation is considered important in the generation of the complex Ca(2+) signals seen inside many cells. But recent findings suggest this bimodal relationship is not always evident and may not apply to some IP(3) receptor isoforms.
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