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  • Title: The influence of intrauterine saline infusion on luteal function and cyclical activity in the mare.
    Author: Neely DP, Hughes JP, Stabenfeldt GH, Evans JW.
    Journal: J Reprod Fertil Suppl; 1975 Oct; (23):235-9. PubMed ID: 1060784.
    Abstract:
    Intrauterine saline infusion in the dioestrous mare shortened the ovulatory interval by inducing premature luteolysis. Plasma progestagen levels began to decrease approximately 1 day after the infusion and had declined to less than 1-0 ng/ml in 4 days. The CL, including others formed from ovulations during dioestrus, must be 4 to 5 days old before intrauterine saline will induce luteolysis. Of 10 mares infused on Day 4 or 5 after ovulation, only six had a shortened ovulatory interval. Of 10 mares infused on Day 6 or 7 after ovulation, seven had a shortened ovulatory interval and three failed to respond due to the occurrence of a dioestrous ovulation near the time of infusion. In those mares which responded to treatment, the interval from saline infusion to the beginning of oestrus and to ovulation was 5 to 6 days and 9 to 10 days, respectively.
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