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  • Title: Effects of progesterone on reproductive function in mares after parturition.
    Author: Loy RG, Hughes JP, Richards WP, Swan SM.
    Journal: J Reprod Fertil Suppl; 1975 Oct; (23):291-5. PubMed ID: 1060792.
    Abstract:
    The injection of 100 mg of progesterone/day from Days 5 to 14 after foaling blocked or delayed oestrus and ovulation in 6/9 mares; the remainder ovulated during treatment without showing oestrus. Urinary oestrogen concentrations in these mares were highest between Days 9 and 15 after foaling but the peak levels were only about half those seen in untreated mares during the post-partum oestrus and ovulation. The injection of 200 mg progesterone/day blocked oestrus and ovulation in two mares but did not depress oestrogen excretion maxima any further. Follicles prevented from developing beyond a cricital stage lost their ability to ovulate after progesterone withdrawal. No significant histological differences were found in endometrial biopsies taken from progesterone-treated and control mares on Days 5, 10 and 15 after foaling. Injection of 100 mg progesterone between Days 1 and 10 after foaling delayed oestrus and ovulation in all six mares. Conception occurred in 8/12 progesterone-treated mares as the result of mating at oestrous periods which were delayed until Days 15 to 28 after foaling.
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