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  • Title: [Neonatal melanoma arising in a giant congenital nevus].
    Author: Benoit-Durafour F, Michel JL, Godard W, Chalencon V, Marzzocchi C, Chalencon F, Cambazard F.
    Journal: Ann Dermatol Venereol; 1999 Nov; 126(11):813-6. PubMed ID: 10612859.
    Abstract:
    INTRODUCTION: Malignant melanoma arising in giant congenital nevus is a well known but rare event. CASE REPORT: A 15 day-old boy with giant congenital nevus all over the left leg was seen for a 6 mm red and bleeding nodule inside the nevus on the inner thigh. Histopathology showed spindle cell malignant melanoma. A 3 cm edge surgical excision was performed with a favorable outcome which persists 5 years later. DISCUSSION: The diagnosis of malignant melanoma is always very difficult in a child, unless metastasis occurs. Histopathologic modifications of childhood malignant melanomas are discussed. Development of malignant melanoma in giant congenital nevus would not appear to exceed 5 p. 100. Nevertheless, early surgical excision is recommended because the nevus is smaller and skin mobilization is easier at this age.
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