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  • Title: [Unusual site of an embryonal rhabdomyosarcoma of the mesenchymal hepatic pedicle].
    Author: Ferlicot S, Quillard J, Chardot C, Caillou B, Oberlin O, Gauthier F, Fabre M.
    Journal: Ann Pathol; 1999 Dec; 19(6):521-4. PubMed ID: 10617810.
    Abstract:
    Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of children. Tumors arising in the extrahepatic biliary tree are extremely rare (less than 1% of cases). In this location, most are RMS of the botryoid type. We report a case of a 10-year-old child with embryonal RMS arising in the mesenchyma of the hepatic pedicle. Most tumor cells were large, round with abundant eosinophilic cytoplasm. A few cells were small round or spindle-shaped. Tumor cells showed positive immunostaining for muscle markers: desmin and sarcomeric actin. Electron microscopy revealed 2 types of cells: some were undifferentiated and others showed striated muscle differentiation features.
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