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  • Title: [Functional loading tests in nephropathy examination in patients recovering from hemorrhagic fever with renal syndrome].
    Author: Pimenov LT, Dudarev MV, Kustarnikov GK.
    Journal: Ter Arkh; 1999; 71(11):26-9. PubMed ID: 10626329.
    Abstract:
    AIM: To characterize nephropathy in patients recovering after hemorrhagic fever with renal syndrome (HFRS) using functional loading tests. MATERIALS AND METHODS: In 65 HFRS convalescents we examined renal function under water deprivation, exercises and studied intraglomerular hemodynamics. RESULTS: After 2-month follow-up renal functional reserve was absent in 34% of the convalescents indicating intraglomerular hypertension. Under water deprivation most of the patients showed persistent tubulointerstitial disorders. Submaximal muscular exercises aggravated glomerular and tubular dysfunction manifesting with microalbuminuria, increased excretory beta 2-microglobulin fraction, low concentration reserve. CONCLUSION: Functional loading tests provide more detailed characterization of renal function in HFRS convalescents.
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