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  • Title: Oral frostbite injury from intentional abuse of a fluorinated hydrocarbon.
    Author: Kuspis DA, Krenzelok EP.
    Journal: J Toxicol Clin Toxicol; 1999; 37(7):873-5. PubMed ID: 10630273.
    Abstract:
    BACKGROUND: A serious but rarely reported complication of halogenated hydrocarbon inhalation abuse is severe mucosal frostbite. CASE REPORT: A 16-year-old male attempted to "get high" by inhaling airbrush propellant which contained 1,1-difluoroethane (CAS #75-376). The patient lost consciousness and upon awakening his lips and tongue were frozen. He suffered first- and second-degree burns of the larynx with vocal cord involvement and first-degree burns of the trachea, main stem bronchi, and esophagus. The oral cavity had second- and third-degree burns which required debridement. CONCLUSION: This case demonstrates the unusual but severe damage that can occur with the abuse of fluorinated hydrocarbons.
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