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  • Title: [A new case of sarcomatous degeneration of the spine in Paget's disease of bone].
    Author: Villiaumey J, Di Menza C, Rotterdam M, Voisin MC, Cherot A.
    Journal: Rev Rhum Mal Osteoartic; 1975 Nov; 42(11):687-91. PubMed ID: 1063431.
    Abstract:
    In referring to a personal observation the authors recall the rarity of malignant degeneration of lesions of the spine caused by Paget's disease. In the majority of cases these consist of multiple centred osteo-sarcomatosis. The lumbar spine is the most often affected. The clinical picture is essentially a syndrome of radiculomedullary compression. Rapid aggravation of the condition usually leads to a neurosurgical operation, which will confirm the existence of the osteo-sarcomatous process. The evolution is always fatal.
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