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  • Title: Plasma levels of tumor necrosis factor-alpha in patients with panic disorder: effect of alprazolam therapy.
    Author: Brambilla F, Bellodi L, Perna G.
    Journal: Psychiatry Res; 1999 Dec 13; 89(1):21-7. PubMed ID: 10643874.
    Abstract:
    Plasma concentrations of tumor necrosis factor-alpha (TNF-alpha) were measured in 10 outpatients with panic disorder, twice (at a 48-h interval) before and twice on days 30-32 of treatment with alprazolam (2-2.5 mg/day), and twice in 10 age- and sex-matched healthy controls. TNF-alpha concentrations did not differ in patients and control subjects, either before therapy or at days 30-32 of therapy. In five patients before therapy, and in three of them after therapy, TNF-alpha values were higher than the maximal concentrations of the cytokine in controls.
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