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  • Title: Angiotropic lymphoma manifesting as a solitary adrenal tumor in a case of ankylosing spondylitis.
    Author: Gau JP, Chiu CF, Liu SM, Hsu HC, Ho CH, Chau WK.
    Journal: Zhonghua Yi Xue Za Zhi (Taipei); 2000 Jan; 63(1):62-5. PubMed ID: 10645053.
    Abstract:
    Angiotropic lymphoma is an extremely rare disease characterized by intravascular accumulation of large neoplastic lymphocytes, with the clinical manifestations of fever, skin lesions and neurologic deficits. We report a patient who developed angiotropic lymphoma after a 10-year history of ankylosing spondylitis. The clinical disease manifested as a unilateral, solitary adrenal tumor, fever and body weight loss. The fever subsided after surgical removal of the adrenal tumor. Systemic chemotherapy was administered postoperatively. The patient was leading an uneventful life 44 months after the initial diagnosis. To our knowledge, this is the first case of angiotropic lymphoma associated with ankylosing spondylitis. It is also the second reported case manifesting with a unilateral solitary adrenal tumor without systemic involvement.
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