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  • Title: [The Italian Registry of Bone Marrow Donors: genetic structure and recruitment strategy].
    Author: Rendine S, Barbanti M, Borelli I, Dall'Omo AM, Roggero S, Sacchi N, Curtoni ES.
    Journal: Ann Ist Super Sanita; 1999; 35(1):21-34. PubMed ID: 10645641.
    Abstract:
    The genetic structure of the Italian bone marrow donor population was analysed by estimating the HLA-A, -B and -DR gene and haplotype frequencies for the total population and for the Italian administrative regions. The haplotype frequencies were used to predict the probability of finding HLA-compatible donors for Italian patients depending on the registry size, and the probability of recruiting in the different Italian regions a donor with a new phenotype. The analysis of these probabilities allows us to propose strategies for donors recruitment in order to increase the phenotypic variability of the registry, then its efficiency.
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