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  • Title: Long-term treatment of portosystemic encephalopathy with oral branched-chain amino acids--a case report.
    Author: Fukuda K, Yao H, Murai K, Ibayashi S, Fujishima M.
    Journal: Fukuoka Igaku Zasshi; 1999 Dec; 90(12):464-9. PubMed ID: 10655667.
    Abstract:
    We treated a 68-year-old male patient of hepatic encephalopathy with oral branched chain amino acids-enriched formula (Aminoleban EN) in addition to lactulose. His encephalopathy was successfully controlled with this therapy for more than a year despite the high blood ammonia levels. Repeated amino acids analyses demonstrated that the deranged branched chain to aromatic amino acids ratio was attenuated with long-term Aminoleban EN administration both in plasma and in cerebrospinal fluid. Oral branched-chain amino acid supplement was very useful in improving the chronic portosystemic or hepatic encephalopathy in this patient.
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