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  • Title: [Primary non-Hodgkin's malignant lymphoma of the adrenal gland. Case report and review of the literature].
    Author: Tazi K, Achour A, Koutani A, Ibn Attya A, Hachimi M, Lakrissa A.
    Journal: Prog Urol; 1999 Dec; 9(6):1102-5. PubMed ID: 10658258.
    Abstract:
    Primary lymphoma of the adrenal gland is an exceptional site for non-Hodgkin's malignant lymphoma, as fewer than 50 cases have been reported in the international literature. To our knowledge, this is the first reported case of intraoperative discovery. The diagnosis of primary adrenal lymphoma can be suggested in the case of bilateral involvement and adrenal insufficiency, but there are no specific clinical or complementary criteria. The main differential diagnoses are adrenal metastases and adenomas. Management is often that of an incidentaloma. Primary NHML of the adrenal gland has a poor prognosis with a mean survival of 15 months. Only one case with a survival of 8 years has been reported in a patient treated with adjuvant radiotherapy, while basic treatment consists of combination chemotherapy. Our patient was treated by adrenalectomy followed by close surveillance.
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