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  • Title: Blood lymphocytes in acute lymphoid leukaemia in remission and in relapse. Predictive value of electrophoretic mobility and refringence.
    Author: Sabolovic D, Pompidou A, Amiel JL.
    Journal: Biomedicine; 1975 Sep 10; 23(7):283-90. PubMed ID: 1066167.
    Abstract:
    Blood lymphocytes were studied during the evolution of acute lymphocytic leukaemia, including remissions and relapses, under chemotherapy and immunotherapy. Lymphoblasts migrate as a uniform population and have a mean electrophoretic mobility of 1.04 mum-sec-1. V-1cm. These lymphoblasts are also refringent. The relapse seems to be preceded by a slowing of the electrophoretic mobility of fast cells and a rise in the percentage of refringent lymphocytes.
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