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  • Title: Emergency repair of type A aortic dissection in type IV Ehlers-Danlos syndrome.
    Author: Ascione R, Gomes WJ, Bates M, Shannon JL, Pope FM, Angelini GD.
    Journal: Cardiovasc Surg; 2000 Jan; 8(1):75-8. PubMed ID: 10661708.
    Abstract:
    Ehlers-Danlos syndrome type IV is a distinctive syndrome in which thin and fragile skin, premature ageing, bruising and scarring are combined with lethal or life-threatening arterial weakness. Aortic rupture either at the aortic root and arch, or sometimes lower down the artery, are particularly characteristic. Even quite minor injury can produce dangerous vascular tearing and damage. Technical difficulties encountered in arterial repair or venous ligature are particularly worrying. The authors report the treatment of a ruptured type A aortic dissection associated with Ehlers-Danlos syndrome where the extreme fragility of the tissues and tendency to bleed posed a difficult task for the surgeon.
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