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  • Title: Frequency and Markov chain analysis of amino-acid sequences of human glutathione reductase.
    Author: Wu G.
    Journal: Biochem Biophys Res Commun; 2000 Feb 24; 268(3):823-6. PubMed ID: 10679290.
    Abstract:
    The amino-acid sequence of human glutathione reductase was measured according to two- and three-amino-acid sequences. The measured frequency and probability were compared with predicted frequency and probability. Of 477 two-amino-acid sequences in human glutathione reductase, 176 (36.897%) and 90 (18.868%) sequences can be explained by the predicted frequency and the predicted probability according to a purely random mechanism. Of 477 measured first Markov transition probabilities for the second amino acid in two-amino-acid sequences, 1 (0.210%) measured first Markov transition probability matches the predicted conditional probability and can therefore be explained by a purely random mechanism. No more than two-amino-acid sequences can be explained by a purely random mechanism.
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