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  • Title: [Morphometric analysis of gap junctions of the cell membrane in human uterine smooth muscle at term].
    Author: Zhang W, Liu J, Zeng Q.
    Journal: Zhonghua Fu Chan Ke Za Zhi; 1998 Apr; 33(4):213-5. PubMed ID: 10682466.
    Abstract:
    OBJECTIVE: To study the changes of the gap junctions (GJS) in the uterine smooth muscle cells at various stages of labor, and its relationship with the onset of labor. METHODS: 18 women (38 to 41 gestational weeks) were divided into three groups: not-in-labor, pre-labor, active in labor and six cases in each group. The uterine myometrium tissues were observed by transmission electron microscopy (TEM) and lanthanum tracing method. RESULTS: The lengths and areas of GJS in uterine corpus and lower segment in the active in labor group were significantly larger than that of the other 2 groups, but there was no significant difference between the not-in-labor and pre-labor groups. The area but not the lengths of GJS in corpus was significant larger than that in the lower segment in the active in labor group. CONCLUSION: The great increase of length and areas of GJS in all parts of the uterine smooth muscle was closely correlated with onset of labor.
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