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  • Title: [Secondary amyloidosis in rheumatoid arthritis. A clinical study of 29 patients].
    Author: Fiter Aresté J, Nolla Solé JM, Gómez Vaquero C, Valverde García J, Roig Escofet D.
    Journal: An Med Interna; 1999 Dec; 16(12):615-9. PubMed ID: 10686712.
    Abstract:
    BACKGROUND: To study the clinical features, outcome and response to therapy in 29 cases of rheumatoid arthritis (RA) with secondary amyloidosis (AA). PATIENTS AND METHOD: Twenty-nine patients with RA and AA who were diagnosed during 11 years. RESULTS: The mean age and the mean duration of RA were 63 +/- 12 years and 15 +/- 7 years respectively. The most common initial clinical feature was renal involvement (83%). Nineteen patients were treated with methotrexate. The mean survival time was 42 +/- 8 months. Eleven patients (38%) have deceased. CONCLUSION: Our data confirms that AA in RA is a serious complication with a bleak prognosis. A normal renal function is a good prognosis indicator.
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