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  • Title: Circumscribed choroidal hemangioma: characteristic features with indocyanine green videoangiography.
    Author: Arevalo JF, Shields CL, Shields JA, Hykin PG, De Potter P.
    Journal: Ophthalmology; 2000 Feb; 107(2):344-50. PubMed ID: 10690837.
    Abstract:
    OBJECTIVE: To determine the characteristic features of indocyanine green videoangiography (ICG-V) of circumscribed choroidal hemangioma. DESIGN: Prospective, observational case series. PARTICIPANTS: Twenty-five eyes of 25 consecutive patients with circumscribed choroidal hemangioma. INTERVENTION: Indocyanine green videoangiography and intravenous fluorescein angiography (IVFA) were prospectively performed and reviewed. The specific features on ICG-V were compared with features of IVFA. MAIN OUTCOME MEASURES: The behavior of circumscribed choroidal hemangioma cases was observed with ICG-V and IVFA. RESULTS: On ICG-V, earliest hyperfluorescence of circumscribed choroidal hemangioma was achieved at a mean of 27.6 seconds (range, 13-62 seconds), whereas maximum hyperfluorescence occurred at 222 seconds (range, 33-707 seconds). In the late frames, all eyes demonstrated a relative decrease in fluorescence, including 18 eyes (72%) that demonstrated "washout" of the dye. Other findings on ICG-V included intrinsic vessels in 19 eyes (76%), a late hyperfluorescent rim in 19 eyes (76%), and late frame hot spots in 14 eyes (56%). On IVFA, the earliest hyperfluorescence was achieved at a mean of 24 seconds (range, 10-66 seconds), whereas maximum hyperfluorescence occurred at a mean of 76.3 seconds (range, 21-720 seconds). Increasing hyperfluorescence in the late frames was found in all cases. Other findings included intrinsic vessels in 12 eyes (48%) and hot spots in the late frames in 9 eyes (36%). CONCLUSIONS: Circumscribed choroidal hemangioma have specific characteristics on ICG-V that are not visualized with IVFA. We believe that ICG-V may become an important noninvasive tool for the diagnosis of choroidal hemangioma.
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