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  • Title: Albendazole treatment for Giardia intestinalis infections in school children.
    Author: Pengsaa K, Sirivichayakul C, Pojjaroen-anant C, Nimnual S, Wisetsing P.
    Journal: Southeast Asian J Trop Med Public Health; 1999 Mar; 30(1):78-83. PubMed ID: 10695793.
    Abstract:
    A randomized controlled trial, 113 school children with Giardia intestinalis infection were treated with albendazole or tinidazole. Albendazole 400 mg once a day x 3 days and tinidazole 50 mg/kg single dose were given orally to 62 and 51 children, respectively. Parasitological cure was documented when there were > or = 2 times negative stool examination for G. intestinalis at 1-2 weeks after therapy. Thirty-one of 62 (50%) children treated with albendazole and 49 of 51 (96.1%) children treated with tinidazole had parasitological cure (p < 0.001). No major side effects were observed except one case in tinidazole group had severe headache for 30 hours. Albendazole appears to be safe and produced a moderate cure rate for G. intestinalis infection when a 3 day anthelmintic regimen is given.
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