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  • Title: A case of chronic granulocytic leukemia in a dog.
    Author: Joiner GN, Fraser CJ, Jardin JH, Trujillo JM.
    Journal: Can J Comp Med; 1976 Apr; 40(2):153-60. PubMed ID: 1069601.
    Abstract:
    A case of chronic granulocytic leukemia was diagnosed in a ten year old miniature poodle and was observed for four and one half years. Methods of diagnosis and characteristic features are described. A persistent granulocytosis with a preponderance of mature forms and the absence of a detectable underlying pyogenic process were key diagnostic features which enabled distinction of this neoplastic process from acute granylocytic leukemia and a leukemoid reaction. Other features included dysplastic granulocytes in various developmental stages, marginal anemia and hyperplastic bone marrow (myeloid elements). No blast crisis occurred. This dog was euthanatized in August 1975.
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