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  • Title: Fluoride deposition in human enamel in vivo from professionally applied fluoride prophylaxis paste.
    Author: Mellberg JR, Nicholson CR, Ripa LW, Barenie J.
    Journal: J Dent Res; 1976; 55(6):976-9. PubMed ID: 1069780.
    Abstract:
    Deciduous teeth were collected from children who received professional prophylaxis with an acidulated phosphate-fluoride (APF) or placebo paste and were analyzed to determine fluoride uptake. Enamel fluoride level was increased by the APF paste approximately 300 ppm at a depth of 2.5 micrometers during the first month after the prophylaxis was administered, after which it returned to pretreatment levels.
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